This disclosure provides a system and method to enable the diagnosis, prognosis and emulation of medical conditions using virtual world environments. The system and method combines probabilistic and pattern recognition mechanisms for both real and virtual world applications to increase health care reach and presence within computational environments. The disclosure describes a system and method that uses physiological measurements and behaviors to diagnose a medical condition. Experimental data, either gathered or generated, provide points for emulation. An emulation algorithm increases the feeling of user presence within a virtual world. Avatar behaviors are mapped to scripts which describe the output of the medical diagnosis and prognosis algorithm. Based on proposed treatment plans, emulations can be run, and the appearance of the avatar altered based on the outcome (e.g., improvement, worsening, etc.).