Invention Grant
- Patent Title: Targeted sequencing of biomolecules by pulling through a liquid-liquid interface with an atomic force microscope
- Patent Title (中): 通过用原子力显微镜拉动液 - 液界面来目标测序生物分子
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Application No.: US13915430Application Date: 2013-06-11
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Publication No.: US08978161B2Publication Date: 2015-03-10
- Inventor: Venkat K. Balagurusamy , Stanislav Polonsky
- Applicant: International Business Machines Corporation
- Applicant Address: US NY Armonk
- Assignee: International Business Machines Corporation
- Current Assignee: International Business Machines Corporation
- Current Assignee Address: US NY Armonk
- Agency: Cantor Colburn LLP
- Agent Anne Dougherty
- Main IPC: G01Q90/00
- IPC: G01Q90/00 ; B82Y35/00 ; C12Q1/68
Abstract:
A mechanism is provided for sequencing a biopolymer. The biopolymer is traversed from a first medium to a second medium. The biopolymer includes bases. As the biopolymer traverses from the first medium to the second medium, different forces are measured corresponding to each of the bases. The bases are distinguished from one another according to the different measured forces which are measured for each of the bases.
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