Invention Grant
- Patent Title: Compositions and methods for brain delivery of analgesic peptides
- Patent Title (中): 用于脑输送镇痛肽的组合物和方法
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Application No.: US13640842Application Date: 2011-04-13
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Publication No.: US08986689B2Publication Date: 2015-03-24
- Inventor: Danica Stanimirovic , Abedelnasser Abulrob , Eric Brunette , Nadia Caram-Salas
- Applicant: Danica Stanimirovic , Abedelnasser Abulrob , Eric Brunette , Nadia Caram-Salas
- Applicant Address: CA Ottawa
- Assignee: National Research Council of Canada
- Current Assignee: National Research Council of Canada
- Current Assignee Address: CA Ottawa
- Agent Sonia Patenaude
- International Application: PCT/CA2011/000416 WO 20110413
- International Announcement: WO2011/127580 WO 20111020
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/00 ; C07K14/575 ; A61K47/48

Abstract:
The present invention relates to non-invasive brain delivery technology for centrally-acting analgesic peptides. Specifically, the invention is directed to compounds comprising an antibody or fragment thereof capable of transmigrating across the blood brain barrier (BBB) and an analgesic peptide. Compositions and methods of using the compounds or compositions are also provided.
Public/Granted literature
- US20130034572A1 COMPOSITIONS AND METHODS FOR BRAIN DELIVERY OF ANALGESIC PEPTIDES Public/Granted day:2013-02-07
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