Invention Grant
US08986725B2 Silicone-peroxide compositions for long-term, controlled oxygen release
有权
用于长期控制氧释放的硅氧烷过氧化物组合物
- Patent Title: Silicone-peroxide compositions for long-term, controlled oxygen release
- Patent Title (中): 用于长期控制氧释放的硅氧烷过氧化物组合物
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Application No.: US13264140Application Date: 2010-04-15
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Publication No.: US08986725B2Publication Date: 2015-03-24
- Inventor: Cherie L. Stabler , Benjamin S. Harrison , Christopher A. Fraker , Eileen Pedraza , Camillo Ricordi
- Applicant: Cherie L. Stabler , Benjamin S. Harrison , Christopher A. Fraker , Eileen Pedraza , Camillo Ricordi
- Applicant Address: US FL Miami US NC Winston-Salem
- Assignee: University of Miami,Wake Forest University Health Sciences
- Current Assignee: University of Miami,Wake Forest University Health Sciences
- Current Assignee Address: US FL Miami US NC Winston-Salem
- Agency: Alston & Bird LLP
- International Application: PCT/US2010/031232 WO 20100415
- International Announcement: WO2010/121024 WO 20101021
- Main IPC: A61K33/00
- IPC: A61K33/00 ; A61P41/00 ; A61K9/00 ; A61L15/44 ; A61L15/18 ; A61L27/54

Abstract:
A composite for delivering extended-release of oxygen is disclosed. The composite can include a biocompatible polymeric support having a plurality of solid peroxide particles suspended therein. The polymer support can exhibit an oxygen tension value of at least 40 mmHg for a period of 14 days. The weight ratio of biocompatible polymeric support to solid peroxide particles can range from 1:1 to 99:1. Also disclosed is a method of using the composite to deliver oxygen to cells in both in vivo and in vitro environments.
Public/Granted literature
- US20120114729A1 SILICONE-PEROXIDE COMPOSITIONS FOR LONG-TERM, CONTROLLED OXYGEN RELEASE Public/Granted day:2012-05-10
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