There is provided a thermal transfer sheet that includes a heat-resistant slipping layer and a colorant layer, the heat-resistant slipping layer and the colorant layer being formable in an in-line process, has excellent heat resistance, and can suppress tailing. The thermal transfer sheet includes a substrate, a colorant layer provided on one surface of the substrate, and a heat-resistant slipping layer provided on the surface of the substrate opposite to the colorant layer, wherein the heat-resistant slipping layer contains at least a binder resin containing an amino group-containing acrylic resin and an epoxysilane, and a slipping agent.