Invention Grant
US08986944B2 Methods and compositions for separating rare cells from fluid samples
有权
用于从流体样品中分离稀有细胞的方法和组合物
- Patent Title: Methods and compositions for separating rare cells from fluid samples
- Patent Title (中): 用于从流体样品中分离稀有细胞的方法和组合物
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Application No.: US11497919Application Date: 2006-08-02
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Publication No.: US08986944B2Publication Date: 2015-03-24
- Inventor: Douglas T. Yamanishi , Paul G. Hujsak , Sara F. Snyder , George Walker , Junquan Xu , Mingxian Huang , Guoliang Tao , Lei Wu , Xiaobo Wang , Joe Ouyang , Charina Schmitigal , Jing Cheng , Jia Xu
- Applicant: Douglas T. Yamanishi , Paul G. Hujsak , Sara F. Snyder , George Walker , Junquan Xu , Mingxian Huang , Guoliang Tao , Lei Wu , Xiaobo Wang , Joe Ouyang , Charina Schmitigal , Jing Cheng , Jia Xu
- Applicant Address: US CA San Diego
- Assignee: Aviva Biosciences Corporation
- Current Assignee: Aviva Biosciences Corporation
- Current Assignee Address: US CA San Diego
- Agency: Morrison & Foerster LLP
- Main IPC: C12Q1/24
- IPC: C12Q1/24 ; C12Q1/68 ; G01N1/40 ; G01N33/569 ; G01N33/574 ; B01L3/00
Abstract:
The present invention includes methods of enriching rare cells, such as cancer cells, from biological samples, such as blood samples. The methods include performing at least one debulking step on a blood sample and selectively removing at least one type undesirable component from the blood sample to obtain a blood sample that is enriched in a rare cell of interest. In some embodiments magnetic beads coupled to specific binding members are used to selectively removed components.
Public/Granted literature
- US20070202536A1 Methods and compositions for separating rare cells from fluid samples Public/Granted day:2007-08-30
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