Invention Grant
- Patent Title: Microorganisms with extended substrate utilization range
- Patent Title (中): 具有延长底物利用范围的微生物
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Application No.: US13183638Application Date: 2011-07-15
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Publication No.: US08986960B2Publication Date: 2015-03-24
- Inventor: Shanna Sichwart , Birgit Haschenhermes , Daniel Bröker , Alexander Steinbüchel , Stephan Hetzler , Perttu Koskinen
- Applicant: Shanna Sichwart , Birgit Haschenhermes , Daniel Bröker , Alexander Steinbüchel , Stephan Hetzler , Perttu Koskinen
- Applicant Address: FI Espoo
- Assignee: Neste Oil Oyj
- Current Assignee: Neste Oil Oyj
- Current Assignee Address: FI Espoo
- Agency: Andrus Intellectual Property Law, LLP
- Priority: EP10169808 20100716
- Main IPC: C12N9/90
- IPC: C12N9/90 ; C12N1/20 ; C12N1/22 ; C12N9/02 ; C12N9/12 ; C12P7/62
Abstract:
Disclosed are microorganisms of the genus Cupriavidus or Ralstonia, which are genetically modified to express phosphomannose isomerase (EC5.3.1.8) and facilitated diffusion protein (EC1.3.1.74) for mannose uptake, and optionally mannofructokinase (EC2.7.1.4). The microorganisms also may be genetically modified to express xylose isomerase (EC 5.3.1.5), xylulokinase (E 2.7.1.17) and xylose proton symporter E or a high affinity ABC-transporter. The genetically modified microorganisms are capable of growing on mannose, xylose, arabinose, glucose, or galactose, or a combination thereof as the carbon source.
Public/Granted literature
- US20120015413A1 Microorganisms with Extended Substrate Utilization Range Public/Granted day:2012-01-19
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