Invention Grant
- Patent Title: Substituted pyridines and pyrimidines
- Patent Title (中): 取代的吡啶和嘧啶
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Application No.: US13519690Application Date: 2010-12-28
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Publication No.: US08986994B2Publication Date: 2015-03-24
- Inventor: Marko Mihovilovic , Michael Schnuerch , Moumita Koley , Karlheinz Hilber , Xaver Koenig
- Applicant: Marko Mihovilovic , Michael Schnuerch , Moumita Koley , Karlheinz Hilber , Xaver Koenig
- Applicant Address: AT Vienna
- Assignee: Technische Universitaet Wien
- Current Assignee: Technische Universitaet Wien
- Current Assignee Address: AT Vienna
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: ATA2044/2009 20091228
- International Application: PCT/AT2010/000495 WO 20101228
- International Announcement: WO2011/079343 WO 20110707
- Main IPC: C12N5/071
- IPC: C12N5/071 ; C07D239/48 ; C07D213/74 ; C12N5/077

Abstract:
Provided are compounds of formula (I) and/or salts thereof, of the class of substituted pyridines and pyrimidines, useful for inducing cardiomyogenesis, a process for producing cardiomyocyte-like cells from mammalian cells by culturing mammalian cells in the presence of the compound of formula (I), the pharmaceutical use of compounds of formula (I) for producing cardiomyocyte-like cells from omnipotent, pluripotent, or lineage committed mammalian cells, and the use of thus produced cardiomyocyte-like cells for treating disorders associated with impaired function of the heart.
Public/Granted literature
- US20120294835A1 SUBSTITUTED PYRIDINES AND PYRIMIDINES Public/Granted day:2012-11-22
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