Invention Grant
- Patent Title: Therapeutic peptides and use thereof against huntington's disease
- Patent Title (中): 治疗性肽及其对亨廷顿舞蹈病的应用
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Application No.: US14111285Application Date: 2012-04-12
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Publication No.: US08987211B2Publication Date: 2015-03-24
- Inventor: Florence Maschat , Marie-Laure Parmentier , Nathalie Bonneaud , Yoan Arribat
- Applicant: Florence Maschat , Marie-Laure Parmentier , Nathalie Bonneaud , Yoan Arribat
- Applicant Address: FR Paris FR Paris FR Montpellier
- Assignee: Centre National de la Recherche Scientifique (CNRS),Institut National de la Sante et de la Recherche Medicale (INSERM),Universite Montpellier 2 Sciences et Techniques
- Current Assignee: Centre National de la Recherche Scientifique (CNRS),Institut National de la Sante et de la Recherche Medicale (INSERM),Universite Montpellier 2 Sciences et Techniques
- Current Assignee Address: FR Paris FR Paris FR Montpellier
- Agency: Young & Thompson
- Priority: FR1153193 20110412
- International Application: PCT/FR2012/050809 WO 20120412
- International Announcement: WO2012/140376 WO 20121018
- Main IPC: A61K38/16
- IPC: A61K38/16 ; A61K38/00 ; A61K48/00 ; A61K38/10 ; C12N15/00 ; C07K5/00 ; C07H21/04 ; C12N15/62 ; C07K14/47 ; C07K4/12
Abstract:
Fusion proteins that contain the fusion of (i) a peptide of less than 100 amino acids comprising a first amino acid sequence comprising AASSG (SEQ ID NO: 1) and a second amino acid sequence comprising XAGXDXXTEXPXS (SEQ ID NO: 2), wherein X designates any amino acid, and (ii) a protein transduction domain (PTD) are provided, along with pharmaceutical compositions containing the fusion protein. The proteins can be used to treat Huntington's disease.
Public/Granted literature
- US20140121167A1 THERAPEUTIC PEPTIDES AND USE THEREOF AGAINST HUNTINGTON'S DISEASE Public/Granted day:2014-05-01
Information query
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