This invention relates to a Dry Running Flexible Impeller Pump and Method of Manufacture designed to provide a flexible impeller pump capable of being run dry for extended periods of time without damage. The pump's components are comprised of low friction materials limiting the heat of friction created by the impeller in use. The impeller is cast of pre-molding silicone substrate containing a quantity of mold release that will not prevent the deposition of a low friction compound coating on the surface of the impeller in a mold that is treated with a low friction industrial coating. Once the impeller is removed from the mold it is solvent cleaned, vacuum baked at a temperature high enough to drive off residual traces of mold release or compounds used to maintain the silicone substrate in suspension, and then coated with a polymer of Poly Para Xylylene by vacuum deposition.