A method for the biological treatment of wastewater containing pollutants, using an aerobic biomass, includes a plurality of successive cycles of a predefined duration in order to achieve pollutants removal efficiency of 90% or higher, each of the cycles including the following steps: —introducing a wastewater effluent containing phosphorus and calcium into a reactor containing biomass; —applying an aerobic phase by introducing into the reactor a gas flow containing oxygen for a predefined length of time, sufficient to form aerobic biomass granules; —decanting the aerobic biomass granules thus formed; —and removing at least part of the treated effluent. After each step of introducing effluent into the reactor, the pH in the reactor is maintained at a value above 8 for a length of time at least equal to 10% of the cycle duration.