Invention Grant
US08999321B2 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
有权
与糖基-tRNA合成酶的蛋白质片段相关的治疗,诊断和抗体组合物的创新发现
- Patent Title: Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
- Patent Title (中): 与糖基-tRNA合成酶的蛋白质片段相关的治疗,诊断和抗体组合物的创新发现
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Application No.: US13809754Application Date: 2011-07-12
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Publication No.: US08999321B2Publication Date: 2015-04-07
- Inventor: Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain Philippe Vasserot , Jeffry D. Watkins , Cheryl L. Quinn , Wing-Sze Lo , John D. Mendlein
- Applicant: Leslie Ann Greene , Kyle P. Chiang , Fei Hong , Alain Philippe Vasserot , Jeffry D. Watkins , Cheryl L. Quinn , Wing-Sze Lo , John D. Mendlein
- Applicant Address: US CA San Diego HK Hong Kong
- Assignee: aTyr Pharma, Inc.,Pangu BioPharma Limited
- Current Assignee: aTyr Pharma, Inc.,Pangu BioPharma Limited
- Current Assignee Address: US CA San Diego HK Hong Kong
- Agency: Cooley LLP
- International Application: PCT/US2011/043756 WO 20110712
- International Announcement: WO2012/021247 WO 20120216
- Main IPC: C12N9/00
- IPC: C12N9/00 ; G01N33/68 ; C12N5/071 ; C07K16/40 ; C12N9/96 ; G01N33/573

Abstract:
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use thereof in diagnostic, drug discovery, research, and therapeutic applications.
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