Invention Grant
US08999367B1 Bioabsorbable substrates and systems that controllably release antimicrobial metal ions
有权
可吸收的底物和可控释放抗微生物金属离子的体系
- Patent Title: Bioabsorbable substrates and systems that controllably release antimicrobial metal ions
- Patent Title (中): 可吸收的底物和可控释放抗微生物金属离子的体系
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Application No.: US14569545Application Date: 2014-12-12
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Publication No.: US08999367B1Publication Date: 2015-04-07
- Inventor: Houdin Dehnad , Paul E. Chirico , Bohdan Wolodymyr Chopko , John Barr , Robert Vincent Mc Cormick , Julie Lucero , Jason A. Jegge
- Applicant: Silver Bullet Therapeutics, Inc.
- Applicant Address: US CA San Jose
- Assignee: Silver Bullet Therapeutics, Inc.
- Current Assignee: Silver Bullet Therapeutics, Inc.
- Current Assignee Address: US CA San Jose
- Agency: Shay Glenn LLP
- Main IPC: A61L31/08
- IPC: A61L31/08 ; A61K33/38 ; A61K9/00 ; A61K33/34 ; A61K33/30 ; A61L31/02

Abstract:
Bioabsorbable substrates having antimicrobial metal ion coatings that are well suited for implantation in to a subject's body to treat and/or prevent infection. In particular, described herein are flexible bioabsorbable filaments that are coated with an anodic metal (e.g., silver and/or zinc and/or copper) that is co-deposited with a cathodic metal (e.g., palladium, platinum, gold, molybdenum, titanium, iridium, osmium, niobium or rhenium) on the filament so that the anodic metal is galvanically released as antimicrobial ions when the apparatus is inserted into a subject's body. The anodic metal may be at least about 30 percent by volume of the coating.
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