Invention Grant
US08999404B2 Phaleria macrocarpa extract, extraction process and its use as cholesteryl ester transferase protein (CETP) inhibitor
有权
Phaleria macrocarpa提取物,提取过程及其用作胆固醇酯转移酶蛋白(CETP)抑制剂
- Patent Title: Phaleria macrocarpa extract, extraction process and its use as cholesteryl ester transferase protein (CETP) inhibitor
- Patent Title (中): Phaleria macrocarpa提取物,提取过程及其用作胆固醇酯转移酶蛋白(CETP)抑制剂
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Application No.: US14111939Application Date: 2012-04-19
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Publication No.: US08999404B2Publication Date: 2015-04-07
- Inventor: Dwi Anggun Septiana Suciptan , Asep Aripin , Raymond R. Tjandrawinata
- Applicant: Dwi Anggun Septiana Suciptan , Asep Aripin , Raymond R. Tjandrawinata
- Applicant Address: ID Tangerang
- Assignee: Pt. Dexa Medica
- Current Assignee: Pt. Dexa Medica
- Current Assignee Address: ID Tangerang
- Agency: Neifeld IP Law, PC
- Priority: IDP00201100229 20110419
- International Application: PCT/IB2012/051954 WO 20120419
- International Announcement: WO2012/143872 WO 20121026
- Main IPC: A01N65/00
- IPC: A01N65/00 ; A61K36/83 ; A61K31/201 ; A61K31/202 ; A61K45/06

Abstract:
An extract and/or herbal fraction and pharmaceutical preparation include extract of Phaleria macrocarpa which for the purpose of this invention, is referred to as DLBS1449. The herbal extract according to the teaching of this invention is effectively applicable to inhibit the expression and activity of Cholesteryl Ester Transferase Protein (CETP), increase HDL cholesterol level, decrease LDL cholesterol level without raising blood pressure therefore it is further applicable in atherosclerosis therapy.
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