Airtight and puncture-resistant multilayer elastomer laminate that can be used in particular in an inflatable article, such as a pneumatic tire for a vehicle, comprising at least the following three layers (phr signifying parts by weight per hundred parts of rubber (elastomer) in each composition considered): as an airtight first layer, a first elastomer composition comprising at least 50 phr of a diene elastomer; as a puncture-resistant second layer, a self-sealing second elastomer composition comprising at least 50 phr of a saturated thermoplastic styrene elastomer and more than 200 phr of an extender oil; as an adhesive third layer or interphase between the above two layers, a third composition comprising at least 30 phr of an unsaturated thermoplastic styrene elastomer.