Invention Grant
- Patent Title: Compositions, kits, and methods for identification, assessment, prevention and treatment of pancreatic adenocarcinoma in humans
- Patent Title (中): 用于人类胰腺腺癌鉴定，评估，预防和治疗的组合物，试剂盒和方法
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Application No.: US11597825Application Date: 2005-05-27
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Publication No.: US08999633B2Publication Date: 2015-04-07
- Inventor: Lynda Chin , Cameron W. Brennan , Ronald A. DePinho , Andrew J. Aguirre
- Applicant: Lynda Chin , Cameron W. Brennan , Ronald A. DePinho , Andrew J. Aguirre
- Applicant Address: US MA Boston
- Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee: Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US MA Boston
- Agency: Foley Hoag LLP
- International Application: PCT/US2005/018850 WO 20050527
- International Announcement: WO2005/118869 WO 20051215
- Main IPC: C12Q1/68
- IPC: C12Q1/68
Abstract:
The invention relates to compositions, kits, and methods for detecting, characterizing, preventing, and treating human pancreatic adenocarcinoma. A variety of chromosomal regions (MCRs) and markers in the MCRs, are provided that are correlated with cancer. In particular, chromosomal regions and markers in the MCR 50.06-62.89 Mb of human chromosome 19, are provided, wherein alterations in the copy number of the MCR and/or alterations in the amount, structure, and/or activity of one or more of the markers in the MCR is correlated with the presence of pancreatic adenocarcinoma.
Public/Granted literature
- US20090297536A1 Compositions, kits, and methods for identification, assessment, prevention and therapy of cancer Public/Granted day:2009-12-03
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