Invention Grant
US08999654B2 Method of identifying a compound for the treatment or prevention of obesity
有权
识别用于治疗或预防肥胖症的化合物的方法
- Patent Title: Method of identifying a compound for the treatment or prevention of obesity
- Patent Title (中): 识别用于治疗或预防肥胖症的化合物的方法
-
Application No.: US12916227Application Date: 2010-10-29
-
Publication No.: US08999654B2Publication Date: 2015-04-07
- Inventor: George A. Gaitanaris , John E. Bergmann , Alexander Gragerov , John Hohmann , Fusheng Li , Linda Madisen , Kellie L. McIlwain , Maria N. Pavlova , Demetri Vassilatis , Hongkui Zeng
- Applicant: George A. Gaitanaris , John E. Bergmann , Alexander Gragerov , John Hohmann , Fusheng Li , Linda Madisen , Kellie L. McIlwain , Maria N. Pavlova , Demetri Vassilatis , Hongkui Zeng
- Applicant Address: US WA Seattle
- Assignee: Omeros Corporation
- Current Assignee: Omeros Corporation
- Current Assignee Address: US WA Seattle
- Agent Tineka J. Quinton; Marcia S. Kelbon
- Main IPC: G01N33/566
- IPC: G01N33/566 ; C07K14/72 ; C12Q1/68 ; C07K14/705 ; A61K38/00
Abstract:
The present invention provides GPCR polypeptides and polynucleotides, recombinant materials, and transgenic mice, as well as methods for their production. The polypeptides and polynucleotides are useful, for example, in methods of diagnosis and treatment of diseases and disorders. The invention also provides methods for identifying compounds (e.g., agonists or antagonists) using the GPCR polypeptides and polynucleotides of the invention, and for treating conditions associated with GPCR dysfunction with the GPCR polypeptides, polynucleotides, or identified compounds. The invention also provides diagnostic assays for detecting diseases or disorders associated with inappropriate GPCR activity or levels.
Public/Granted literature
- US20110214189A1 G PROTEIN COUPLED RECEPTORS AND USES THEREOF Public/Granted day:2011-09-01
Information query
IPC分类:
