Invention Grant
US08999655B2 Increase of myeloid microvesicles in the cerebrospinal fluid as biomarker of microglia/macrophage activation in neurological disorders
有权
作为神经系统疾病中小胶质细胞/巨噬细胞活化的生物标志物，脑脊液中骨髓微泡的增加
- Patent Title: Increase of myeloid microvesicles in the cerebrospinal fluid as biomarker of microglia/macrophage activation in neurological disorders
- Patent Title (中): 作为神经系统疾病中小胶质细胞/巨噬细胞活化的生物标志物，脑脊液中骨髓微泡的增加
-
Application No.: US13581646Application Date: 2011-03-03
-
Publication No.: US08999655B2Publication Date: 2015-04-07
- Inventor: Claudia Verderio , Michela Matteoli , Roberto Furlan
- Applicant: Claudia Verderio , Michela Matteoli , Roberto Furlan
- Applicant Address: IT Rome IT Milan IT Milan
- Assignee: Consiglio Nazionale delle Ricerche,Universita degli Studi di Milano,Ospedale San Raffaele S.r.l.
- Current Assignee: Consiglio Nazionale delle Ricerche,Universita degli Studi di Milano,Ospedale San Raffaele S.r.l.
- Current Assignee Address: IT Rome IT Milan IT Milan
- Agency: Lucas & Mercanti, LLP
- International Application: PCT/IB2011/050915 WO 20110303
- International Announcement: WO2011/107962 WO 20110909
- Main IPC: G01N33/50
- IPC: G01N33/50 ; G01N33/566 ; G01N33/68 ; G01N33/98 ; G01N23/22 ; C12Q1/68
Abstract:
The present invention relates to a method for the diagnostic and/or prognostic of a neurological disease characterized by an inflammation process in a subject comprising measuring the amount of myeloid derived microvesicles in a cerebrospinal fluid sample obtained from the subject. The invention further relates to a method for predicting and/or monitoring the efficacy of a treatment for a neurological pathology or for monitoring a neurological disease progression.
Public/Granted literature
Information query
IPC分类:
