Invention Grant
- Patent Title: Detection and visualization of the cell cycle in living cells
- Patent Title (中): 活细胞中细胞周期的检测和可视化
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Application No.: US13382302Application Date: 2010-07-06
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Publication No.: US08999669B2Publication Date: 2015-04-07
- Inventor: Ulrich Rothbauer , Heinrich Leonhardt , Kourosh Zolghadr , Tina Romer , Katrin Schmidthals
- Applicant: Ulrich Rothbauer , Heinrich Leonhardt , Kourosh Zolghadr , Tina Romer , Katrin Schmidthals
- Applicant Address: DE Munich
- Assignee: Ludwig-Maximilians Universitat München
- Current Assignee: Ludwig-Maximilians Universitat München
- Current Assignee Address: DE Munich
- Agency: DT Ward, P.C.
- Agent Donna T. Ward; Heng Zhu
- Priority: EP09008827 20090706
- International Application: PCT/EP2010/059622 WO 20100706
- International Announcement: WO2011/003896 WO 20110113
- Main IPC: C12P21/06
- IPC: C12P21/06 ; C07K16/18 ; G01N33/58 ; G01N33/68
Abstract:
The present invention relates to a nucleic acid molecule encoding a polypeptide specifically binding to proliferating cell nuclear antigen (PCNA). The present invention also relates to a vector comprising the nucleic acid molecule of the invention, a host cell comprising the nucleic acid molecule of or the vector of the invention and a method of detecting the amount and/or location of PCNA in living cells, a method of screening for compounds having an effect on the cell cycle.
Public/Granted literature
- US20120149028A1 DETECTION AND VISUALIZATION OF THE CELL CYCLE IN LIVING CELLS Public/Granted day:2012-06-14
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