Invention Grant
US08999937B2 Glucocorticoid induced leucine zipper mimetics as therapeutic agents in multiple sclerosis
有权
糖皮质激素诱导的亮氨酸拉链模拟物作为多发性硬化症中的治疗剂
- Patent Title: Glucocorticoid induced leucine zipper mimetics as therapeutic agents in multiple sclerosis
- Patent Title (中): 糖皮质激素诱导的亮氨酸拉链模拟物作为多发性硬化症中的治疗剂
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Application No.: US14001716Application Date: 2012-02-28
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Publication No.: US08999937B2Publication Date: 2015-04-07
- Inventor: Mythily Srinivasan
- Applicant: Mythily Srinivasan
- Applicant Address: US IN Indianapolis
- Assignee: Indiana University Research and Technology Corporation
- Current Assignee: Indiana University Research and Technology Corporation
- Current Assignee Address: US IN Indianapolis
- Agency: Barnes & Thornburg LLP
- International Application: PCT/US2012/026962 WO 20120228
- International Announcement: WO2012/118821 WO 20120907
- Main IPC: C07K14/47
- IPC: C07K14/47 ; A61K38/07 ; A61K38/08 ; A61K38/10 ; A61K38/16
Abstract:
Polypeptide compositions that mimic the activity of glucocorticoid induced leucine zipper (GILZ) on the immune system are described. Also described is a method of treating multiple sclerosis using compositions comprising GILZ or lower molecular weight polypeptides with structural relationships to GILZ.
Public/Granted literature
- US20130338077A1 GLUCOCORTICOID INDUCED LEUCINE ZIPPER MIMETICS AS THERAPEUTIC AGENTS IN MULTIPLE SCLEROSIS Public/Granted day:2013-12-19
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