Invention Grant
- Patent Title: Acyl piperazine derivatives as TTX-S blockers
- Patent Title (中): 酰基哌嗪衍生物作为TTX-S阻断剂
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Application No.: US13814716Application Date: 2011-08-09
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Publication No.: US08999974B2Publication Date: 2015-04-07
- Inventor: Mikiko Morita , Shuzo Watanabe
- Applicant: Mikiko Morita , Shuzo Watanabe
- Applicant Address: JP Aichi
- Assignee: Raqualia Pharma Inc.
- Current Assignee: Raqualia Pharma Inc.
- Current Assignee Address: JP Aichi
- Agency: Marshall, Gerstein & Borun LLP
- International Application: PCT/JP2011/004515 WO 20110809
- International Announcement: WO2012/020567 WO 20120216
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/506 ; C07D239/47 ; A61K45/06 ; C07D401/14 ; C07D405/12 ; C07D409/12 ; C07D413/12 ; C07D417/12 ; A61K31/517 ; A61K31/538 ; C07D401/12 ; C07D403/04 ; C07D417/14 ; C07D471/04 ; C07D487/08 ; C07D495/04
Abstract:
The present invention relates to acyl piperazine derivatives which have blocking activities of voltage gated sodium channels as the TTX-S channels, and which are useful in the treatment or prevention of disorders and diseases in which voltage gated sodium channels are involved. The invention also relates to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which voltage gated sodium channels are involved.
Public/Granted literature
- US20130150356A1 Acyl Piperazine Derivatives as TTX-S Blockers Public/Granted day:2013-06-13
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