Invention Grant
- Patent Title: Modulators of cystic fibrosis transmembrane conductance regulator
- Patent Title (中): 囊性纤维化跨膜电导调节剂的调节剂
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Application No.: US14100748Application Date: 2013-12-09
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Publication No.: US08999976B2Publication Date: 2015-04-07
- Inventor: Hayley Binch , Dennis Hurley , Lev T. D. Fanning , Peter D. J. Grootenhuis , Martyn Botfield , Fredrick Van Goor
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Michele A. Kercher-DiVerdi
- Main IPC: C07D279/16
- IPC: C07D279/16 ; A61K31/5415 ; C07D265/36 ; C07D413/12 ; A61K31/538 ; A61K45/06
Abstract:
The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating diseases using such CFTR modulators.
Public/Granted literature
- US20140235625A1 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR Public/Granted day:2014-08-21
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