Invention Grant
- Patent Title: Precursors of glutamate derivatives
- Patent Title (中): 谷氨酸衍生物的前体
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Application No.: US14115127Application Date: 2012-04-30
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Publication No.: US09000037B2Publication Date: 2015-04-07
- Inventor: Christina Hultsch , Michael Harre , Filip Novak , Mathias Berndt , Matthias Friebe , Heribert Schmitt-Willich , Dae Yoon Chi , Byoung Se Lee , Sang Don Park
- Applicant: Christina Hultsch , Michael Harre , Filip Novak , Mathias Berndt , Matthias Friebe , Heribert Schmitt-Willich , Dae Yoon Chi , Byoung Se Lee , Sang Don Park
- Applicant Address: CH Matran
- Assignee: Piramal Imaging SA
- Current Assignee: Piramal Imaging SA
- Current Assignee Address: CH Matran
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: EP11075077 20110503
- International Application: PCT/EP2012/057884 WO 20120430
- International Announcement: WO2012/150204 WO 20121108
- Main IPC: A61K31/04
- IPC: A61K31/04 ; C07C309/77 ; C07B59/00 ; C07C227/16 ; C07C227/18 ; C07C229/24 ; C07C309/73 ; C07C309/74 ; C07D215/36 ; C07C229/36 ; C07C303/28
Abstract:
This invention relates to novel precursors suitable for 18F radiolabeling of glutamate derivatives, methods for preparing such compounds and its intermediates, compositions comprising such compounds, kits comprising such compounds or compositions and methods for 18F radiolabeling of glutamate derivatives wherein the obtained 18F radiolabeled glutamate derivatives are suitable for diagnostic imaging by Positron Emission Tomography (PET) of proliferative diseases e.g. tumor in mammals.
Public/Granted literature
- US20140243532A1 NOVEL PRECURSORS OF GLUTAMATE DERIVATIVES Public/Granted day:2014-08-28
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