Invention Grant
- Patent Title: Fused pyrimidine-dione derivatives as TRPA1 modulators
- Patent Title (中): 融合的嘧啶二酮衍生物作为TRPA1调节剂
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Application No.: US14079932Application Date: 2013-11-14
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Publication No.: US09000159B2Publication Date: 2015-04-07
- Inventor: Sachin Sundarlal Chaudhari , Sukeerthi Kumar , Abraham Thomas , Nisha Parag Patil , Ashok Bhausaheb Kadam , Vishal Govindrao Deshmukh , Sachin Vasantrao Dhone , Rajendra Prakash Chikhale , Neelima Khairatkar-Joshi , Indranil Mukhopadhyay
- Applicant: Glenmark Pharmaceuticals, S.A.
- Applicant Address: CH La Chaux-de-Fonds
- Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee: Glenmark Pharmaceuticals S.A.
- Current Assignee Address: CH La Chaux-de-Fonds
- Agency: Pergament Gilman & Cepeda LLP
- Agent Milagros A. Cepeda; Edward D. Pergament
- Priority: IN665/MUM/2009 20090323; IN2211/MUM/2009 20090923; IN2212/MUM/2009 20090923; IN2891/MUM/2009 20091215; IN2892/MUM/2009 20091215
- Main IPC: C07D487/00
- IPC: C07D487/00 ; C07D487/04
Abstract:
The invention described herein relates to novel fused pyrimidinediones derivatives of formula (I) which are TRPA (Transient Receptor Potential subfamily A) modulators. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders modulated by TRPA1 (Transient Receptor Potential subfamily A, member 1). This invention also provides processes for preparing compounds described herein, intermediates used in their synthesis, pharmaceutical compositions thereof, and methods for treating or preventing diseases, conditions and/or disorders modulated by TRPA1.
Public/Granted literature
- US20140128603A1 FUSED PYRIMIDINE-DIONE DERIVATIVES AS TRPA1 MODULATORS Public/Granted day:2014-05-08
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