Invention Grant
US09000173B2 Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity
有权
具有毒蕈碱受体拮抗剂和二肾上腺素受体激动剂活性的二酰胺化合物
- Patent Title: Diamide compounds having muscarinic receptor antagonist and β2 adrenergic receptor agonist activity
- Patent Title (中): 具有毒蕈碱受体拮抗剂和二肾上腺素受体激动剂活性的二酰胺化合物
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Application No.: US14327853Application Date: 2014-07-10
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Publication No.: US09000173B2Publication Date: 2015-04-07
- Inventor: Adam D. Hughes , Yan Chen , John R. Jacobsen , Eric L. Stangeland , Rose Yen
- Applicant: Adam D. Hughes , Yan Chen , John R. Jacobsen , Eric L. Stangeland , Rose Yen
- Applicant Address: US CA South San Francisco
- Assignee: Theravance Respiratory Company, LLC
- Current Assignee: Theravance Respiratory Company, LLC
- Current Assignee Address: US CA South San Francisco
- Agent Jeffrey A. Hagenah
- Main IPC: C07D401/12
- IPC: C07D401/12 ; A61K45/06 ; A61K31/444 ; A61K31/4709 ; A61K31/56
Abstract:
This invention relates to a compound of formula I: or a pharmaceutically acceptable salt thereof. Such compounds possess both muscarinic receptor antagonist and β2 adrenergic receptor agonist activities. The invention also relates to pharmaceutical compositions comprising such compounds, processes and intermediates for preparing such compounds, and methods of using such compounds as bronchodilating agents to treat pulmonary disorders.
Public/Granted literature
- US20140323733A1 DIAMIDE COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY Public/Granted day:2014-10-30
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