A system and method for performing hand hygiene compliance. The method includes receiving a notification that an individual has entered a physical location. The notification is received by a node in a wireless mesh network that includes a plurality of nodes corresponding to objects in the physical location. A hand hygiene protocol is identified for the individual. It is determined that the individual has not followed the hand hygiene protocol. The determining is performed by software executing on the nodes in the wireless mesh network and responsive to a previous and a current location of the individual relative to the objects in the physical location. The individual is notified in response to determining that the individual has not followed the hand hygiene protocol.