An energy-efficient touch panel control device includes a touch panel, a buffer memory, an analog to digital conversion unit, for converting analog output voltage to digital trace data and storing the digital trace data in the buffer memory, and according to a control signal, switching an operating mode, an operation unit, generating a detecting result according to the digital trace data, switching the operating mode according to an interrupt signal, and including a mode control unit, for generating the control signal according to the interrupt signal, and a host interface unit.