A method and system for isochronous data stream management in high speed audio/video networks. One implementation comprises isochronous communication management between audio/video (AV) devices by maintaining forwarding information for forwarding data between AV devices, wherein each AV device includes multiple I/O ports for connecting the AV device to another AV device via a communication link including multiple communication lanes. The forwarding information is utilized to communicate AV path set-up request and response control messages between a source AV device and a destination AV device via said communication link, and allocating isochronous communication resources for AV data streaming, for establishing AV path streams for bi-directional isochronous AV data streaming between the source and destination AV devices.