A computer-implemented method for replacing sensitive information stored within non-secure environments with secure references to the same may include (1) identifying sensitive information stored within a non-secure environment on a computing device, (2) removing the sensitive information from the non-secure environment, (3) storing the sensitive information within a secure environment, (4) replacing the sensitive information originally stored within the non-secure environment with a reference that identifies the sensitive information stored within the secure environment, (5) identifying a request to access at least a portion of the sensitive information identified in the reference, (6) determining that at least a portion of the request satisfies a data-loss-prevention policy, and then (7) providing access to at least a portion of the sensitive information via the secure environment. Various other systems, methods, and computer-readable media are also disclosed.