Invention Grant
- Patent Title: Methods of treating cancer by administering EMP2 antibodies
- Patent Title (中): 通过施用EMP2抗体治疗癌症的方法
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Application No.: US13684901Application Date: 2012-11-26
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Publication No.: US09011857B2Publication Date: 2015-04-21
- Inventor: Jonathan Braun , Lynn K. Gordon , Kaori Shimazaki , Madhuri Wadehra , Kathy A. Kelly , Anna M. Wu
- Applicant: The Regents of The University of California
- Applicant Address: US CA Oakland
- Assignee: The Regents of The University of California
- Current Assignee: The Regents of The University of California
- Current Assignee Address: US CA Oakland
- Agency: Morgan, Lewis & Bockius LLP
- Agent Annette S. Parent
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/395 ; C07K16/30 ; C07K16/12 ; C07K16/28 ; A61K45/06
Abstract:
The present invention provides methods and compositions useful in the treatment or prevention of Chlamydia infections and cancer. The methods and compositions inhibit the entry of Chlamydia into a host cell expressing EMP2 by interfering with the interaction between the Chlamydia and EMP2. The methods and compositions target cancers which express or overexpress EMP2 nucleic acids and polypeptides by targeting EMP2.
Public/Granted literature
- US20130230527A1 EMP2 ANTIBODIES AND THEIR THERAPEUTIC USES Public/Granted day:2013-09-05
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