Invention Grant
- Patent Title: Dipeptides to enhance yield and viability from cell cultures
- Patent Title (中): 二肽以增强细胞培养物的产量和活力
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Application No.: US13814397Application Date: 2011-08-05
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Publication No.: US09012178B2Publication Date: 2015-04-21
- Inventor: Sohye Kang , Rohini Deshpande , Rebecca E. McCoy , Leslie P. Miranda , Arvia E. Morris
- Applicant: Sohye Kang , Rohini Deshpande , Rebecca E. McCoy , Leslie P. Miranda , Arvia E. Morris
- Applicant Address: US CA Thousand Oaks
- Assignee: Amgen Inc.
- Current Assignee: Amgen Inc.
- Current Assignee Address: US CA Thousand Oaks
- Agent Kathleen Fowler
- International Application: PCT/US2011/046850 WO 20110805
- International Announcement: WO2012/019160 WO 20120209
- Main IPC: C12P21/04
- IPC: C12P21/04 ; C07K16/00 ; C07K5/062 ; C07K5/065 ; C07K5/072 ; C12N5/00
Abstract:
The present invention relates to the culture of animal cells in serum-free culture medium. The present invention provides particular dipeptides that can improve recombinant protein production and cell viability in such cultures, especially in the absence of peptones.
Public/Granted literature
- US20130189737A1 DIPEPTIDES TO ENHANCE YIELD AND VIABILITY FROM CELL CULTURES Public/Granted day:2013-07-25
Information query
