Invention Grant
US09012214B2 Recombinant measles viruses expressing epitopes of antigens of RNA viruses—use for the preparation of vaccine compositions
有权
表达RNA病毒抗原表位的重组麻疹病毒 - 用于制备疫苗组合物
- Patent Title: Recombinant measles viruses expressing epitopes of antigens of RNA viruses—use for the preparation of vaccine compositions
- Patent Title (中): 表达RNA病毒抗原表位的重组麻疹病毒 - 用于制备疫苗组合物
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Application No.: US12700621Application Date: 2010-02-04
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Publication No.: US09012214B2Publication Date: 2015-04-21
- Inventor: Frédéric Tangy , Clarisse Lorin , Lucile Mollet , Frédéric Delebecque
- Applicant: Frédéric Tangy , Clarisse Lorin , Lucile Mollet , Frédéric Delebecque
- Applicant Address: FR Paris FR Paris
- Assignee: Institut Pasteur,Centre National de la Recherche Scientifique
- Current Assignee: Institut Pasteur,Centre National de la Recherche Scientifique
- Current Assignee Address: FR Paris FR Paris
- Agency: Law Office of Salvator Arrigo and Scott Lee LLP
- Priority: EP02291550 20020620
- Main IPC: C12Q1/70
- IPC: C12Q1/70 ; C07H21/04 ; C07K14/005 ; A61K47/48 ; C12N15/86 ; A61K39/00
Abstract:
The invention relates to a recombinant measles virus expressing a heterologous amino acid sequence derived from an antigen of a determined RNA virus, the recombinant measles virus being capable of eliciting a humoral and/or cellular immune response against measles virus or against the RNA virus or against both measles virus and against the RNA virus. It also relates to the use of the recombinant measles virus for the preparation of immunogenic compositions.
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