Invention Grant
- Patent Title: Bicyclic cyclohexose nucleic acid analogs
- Patent Title (中): 双环环己糖核酸类似物
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Application No.: US13388115Application Date: 2010-08-05
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Publication No.: US09012421B2Publication Date: 2015-04-21
- Inventor: Michael T. Migawa , Punit P. Seth , Eric E. Swayze , Bruce S. Ross , Quanlai Song , Mingming Han
- Applicant: Michael T. Migawa , Punit P. Seth , Eric E. Swayze , Bruce S. Ross , Quanlai Song , Mingming Han
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc. Patent Dept.
- Agent Casimir Jones, S.C.
- International Application: PCT/US2010/044549 WO 20100805
- International Announcement: WO2011/017521 WO 20110210
- Main IPC: A61K31/712
- IPC: A61K31/712 ; C07H19/06 ; C07H21/00 ; C12N5/071 ; C07H19/16
Abstract:
The present invention provides bicyclic cyclohexose nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.
Public/Granted literature
- US20120172414A1 BICYCLIC CYCLOHEXOSE NUCLEIC ACID ANALOGS Public/Granted day:2012-07-05
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