Invention Grant
- Patent Title: Salts and polymorphic forms of Afatinib
- Patent Title (中): 盐酸盐和多形态阿片碱
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Application No.: US13989603Application Date: 2011-11-23
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Publication No.: US09012464B2Publication Date: 2015-04-21
- Inventor: Ramesh Matioram Gidwani , Channaveerayya Hiremath , Manoj Dalsingar Yadav , Wolfgang Albrecht , Dirk Fischer
- Applicant: Ramesh Matioram Gidwani , Channaveerayya Hiremath , Manoj Dalsingar Yadav , Wolfgang Albrecht , Dirk Fischer
- Applicant Address: DE Ulm
- Assignee: Ratiopharm GmbH
- Current Assignee: Ratiopharm GmbH
- Current Assignee Address: DE Ulm
- Agency: Baker & Hostetler LLP
- Priority: IN2807/DEL/2010 20101125
- International Application: PCT/US2011/062031 WO 20111123
- International Announcement: WO2012/121764 WO 20120913
- Main IPC: C07D405/12
- IPC: C07D405/12

Abstract:
Afatinib salts and crystalline forms thereof are described in the present application and processes for their preparation. Crystalline forms of Afatinib are also described in the present application and processes for their preparation. The present invention also includes pharmaceutical compositions of such Afatinib salts and crystalline forms thereof or crystalline forms of Afatinib, methods of their preparation and the use thereof in the treatment of a patient in need thereof.
Public/Granted literature
- US20140051713A1 NOVEL SALTS AND POLYMORPHIC FORMS OF AFATINIB Public/Granted day:2014-02-20
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