Invention Grant
- Patent Title: One pot process for producing 6-hydroxyl nal-opiate
- Patent Title (中): 一锅法制备6-羟基正缬氨酸
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Application No.: US13762431Application Date: 2013-02-08
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Publication No.: US09012468B2Publication Date: 2015-04-21
- Inventor: Peter X. Wang , Tao Jiang
- Applicant: Mallinckrodt LLC
- Applicant Address: US MO Hazelwood
- Assignee: Mallinckrodt LLC
- Current Assignee: Mallinckrodt LLC
- Current Assignee Address: US MO Hazelwood
- Main IPC: C07D221/22
- IPC: C07D221/22 ; C07D271/00 ; C07D491/00 ; C07D498/00 ; C07D513/00 ; C07D515/00 ; C07D489/00 ; A01N43/42 ; A61K31/42 ; C07D489/08 ; C07D489/02
Abstract:
The present invention provides processes for preparing nal-opiates without the isolation of intermediates. In general, the process provides for alkylation and reduction in the same pot to give the nal-opiate.
Public/Granted literature
- US20130203999A1 One Pot Process for Producing 6-Hydroxyl Nal-Opiate Public/Granted day:2013-08-08
Information query
