Invention Grant
- Patent Title: Crystalline naloxol-peg conjugate
- Patent Title (中): 结晶纳洛酮栓缀合物
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Application No.: US13823953Application Date: 2011-09-29
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Publication No.: US09012469B2Publication Date: 2015-04-21
- Inventor: Bengt Leonard Åslund , Carl-Johan Aurell , Martin Hans Bohlin , Eric Thomas Healy , David Richard Jensen , David Thomas Jonaitis , Stephan Parent , Tesfai Sebhatu , Bo Ingvar Ymén
- Applicant: Bengt Leonard Åslund , Carl-Johan Aurell , Martin Hans Bohlin , Eric Thomas Healy , David Richard Jensen , David Thomas Jonaitis , Stephan Parent , Tesfai Sebhatu , Bo Ingvar Ymén
- Applicant Address: SE Sodertalje US CA San Francisco
- Assignee: AstraZeneca AB,Nektar Therapeutics
- Current Assignee: AstraZeneca AB,Nektar Therapeutics
- Current Assignee Address: SE Sodertalje US CA San Francisco
- Agency: Jones Day
- International Application: PCT/SE2011/051161 WO 20110929
- International Announcement: WO2012/044243 WO 20120405
- Main IPC: A61K31/485
- IPC: A61K31/485 ; C07D489/04 ; A61K47/48 ; C07C51/41 ; C07C55/07

Abstract:
Naloxol-polyethlyene glycol conjugates of the formula: are provided in oxalate or phosphate salt forms including crystalline forms. Methods of preparing the salt forms and pharmaceutical compositions comprising the salt forms are also provided.
Public/Granted literature
- US20150038524A1 CRYSTALLINE NALOXOL-PEG CONJUGATE Public/Granted day:2015-02-05
Information query
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