Invention Grant
US09012489B2 Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament
有权
苯基-3-氮杂 - 双环[3.1.0]己-3-基 - 甲酮及其作为药物的用途
![Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament](/docs/US/2015-04-21/US09012489B2/abs.jpg.600x600.jpg)
- Patent Title: Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament
- Patent Title (中): 苯基-3-氮杂 - 双环[3.1.0]己-3-基 - 甲酮及其作为药物的用途
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Application No.: US13560063Application Date: 2012-07-27
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Publication No.: US09012489B2Publication Date: 2015-04-21
- Inventor: Riccardo Giovannini , Barbara Bertani , Marco Ferrara , Iain Lingard , Rocco Mazzaferro , Holger Rosenbrock
- Applicant: Riccardo Giovannini , Barbara Bertani , Marco Ferrara , Iain Lingard , Rocco Mazzaferro , Holger Rosenbrock
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Alan R. Stempel
- Priority: EP11176468 20110803
- Main IPC: A61K31/40
- IPC: A61K31/40 ; A61K31/41 ; C07D413/04 ; C07D209/52 ; C07D417/04 ; C07D403/04 ; C07D413/14 ; C07D401/04 ; C07D471/04
![Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament](/abs-image/US/2015/04/21/US09012489B2/abs.jpg.150x150.jpg)
Abstract:
Substituted phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones which are glycine transporter-1 (GlyT1) inhibitors. These are useful for the treatment of schizophrenia, Alzheimer's Disease and other neurological and psychiatric disorders.
Public/Granted literature
- US20130197011A1 Phenyl-3-aza-bicyclo[3.1.0]hex-3-yl-methanones and the use thereof as medicament Public/Granted day:2013-08-01
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