Invention Grant
- Patent Title: PKC-ε activator
- Patent Title (中): PKC-&egr 活化剂
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Application No.: US13885751Application Date: 2011-11-15
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Publication No.: US09012500B2Publication Date: 2015-04-21
- Inventor: Tomoyuki Nishizaki , Akito Tanaka
- Applicant: Tomoyuki Nishizaki , Akito Tanaka
- Applicant Address: JP Kobe-shi
- Assignee: Nishizaki Bioinformation Research Institute
- Current Assignee: Nishizaki Bioinformation Research Institute
- Current Assignee Address: JP Kobe-shi
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2010-255967 20101116
- International Application: PCT/JP2011/076302 WO 20111115
- International Announcement: WO2012/067111 WO 20120524
- Main IPC: A61K31/235
- IPC: A61K31/235 ; C07C53/132

Abstract:
The present invention aims to obtain an optical isomer of DCP-LA, which shows more superior activity and is suitable for clinical utilization, and provide an agent having a superior PKC-ε activation action, a prophylactic and/or therapeutic agent for neurotransmitter release disorders, and a prophylactic and/or therapeutic agent for neuropsychiatric diseases, which contain the isomer as an active ingredient.A compound represented by the following formula: or a pharmaceutically acceptable salt thereof, and a selective PKC-ε activator containing same as an active ingredient, and is the like.
Public/Granted literature
- US20130331454A1 PKC-EPSILON ACTIVATOR Public/Granted day:2013-12-12
Information query