Invention Grant
US09012604B2 Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling
有权
三唑烷衍生物或其药学上可接受的盐，用于增强氟-18标记
- Patent Title: Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling
- Patent Title (中): 三唑烷衍生物或其药学上可接受的盐，用于增强氟-18标记
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Application No.: US13983053Application Date: 2012-02-01
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Publication No.: US09012604B2Publication Date: 2015-04-21
- Inventor: Jae Min Jeong , Dinesh Shetty , Dong Soo Lee , June-Key Chung , Myung Chul Lee
- Applicant: Jae Min Jeong , Dinesh Shetty , Dong Soo Lee , June-Key Chung , Myung Chul Lee
- Applicant Address: KR Seoul
- Assignee: Snur & DB Foundation
- Current Assignee: Snur & DB Foundation
- Current Assignee Address: KR Seoul
- Agency: Agris & von Natzmer, LLP
- Agent Cheryl H. Agris
- Priority: KR10-2011-0010202 20110201
- International Application: PCT/KR2012/000790 WO 20120201
- International Announcement: WO2012/105814 WO 20120809
- Main IPC: A61K38/12
- IPC: A61K38/12 ; C07K5/00 ; C07K7/00 ; C07K16/00 ; C07K17/00 ; C07D255/02 ; A61K51/04 ; C07K7/64
Abstract:
The present invention relates to a triazanonane derivative indicated by the chemical formula 1 below, or a pharmaceutically acceptable salt thereof, and a method for preparing same, and the triazanonane derivative according to the present invention forms a complex with a metal-fluoride and displays an effect of increasing the labeling efficiency up to 78-90% when labeling F-18, thus enabling use in various radioactive medicine labeling (In the chemical formula 1, R1, R2, A. E. X, n and m are as defined in the present description.)
Public/Granted literature
- US20130317196A1 TRIAZANONANE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR ENHANCED FLUORINE-18 LABELING Public/Granted day:2013-11-28
Information query
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