Invention Grant
US09012610B2 Diagnostic kit for IGFBP-4 proteolytic fragments in a patient sample
有权
用于患者样本中IGFBP-4蛋白水解片段的诊断试剂盒
- Patent Title: Diagnostic kit for IGFBP-4 proteolytic fragments in a patient sample
- Patent Title (中): 用于患者样本中IGFBP-4蛋白水解片段的诊断试剂盒
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Application No.: US13381230Application Date: 2010-06-29
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Publication No.: US09012610B2Publication Date: 2015-04-21
- Inventor: Alexey G. Katrukha , Alexander B. Postnikov , Tatiana I. Solovyeva , Alexey V. Kharitonov
- Applicant: Alexey G. Katrukha , Alexander B. Postnikov , Tatiana I. Solovyeva , Alexey V. Kharitonov
- Applicant Address: FI Turku
- Assignee: Hytest Ltd.
- Current Assignee: Hytest Ltd.
- Current Assignee Address: FI Turku
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: FI20095733 20090629
- International Application: PCT/FI2010/050559 WO 20100629
- International Announcement: WO2011/001029 WO 20110106
- Main IPC: C07K16/18
- IPC: C07K16/18 ; C07K16/22 ; G01N33/574 ; G01N33/50
Abstract:
The present invention relates to a method for diagnosing a cardiovascular or cancer disease by detecting IGFBP-4 (Insulin-like Growth Factor Binding Protein-4) fragments in a patient sample. Antibodies specifically recognizing novel epitopes originated by enzyme-dependent cleavage of IGFBP-4 are also disclosed.
Public/Granted literature
- US20120178113A1 DETECTION OF IGFBP-4 FRAGMENTS AS A DIAGNOSTIC METHOD Public/Granted day:2012-07-12
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