An image reporting method is provided. The image reporting method comprises the steps of retrieving an image representation of a sample structure from an image source; mapping a generic structure to the sample structure, the generic structure being related to the sample structure and having at least coordinate data defined therein; determining one or more regions of interest within the sample structure based on content of the image representation of the sample structure; associating an annotation to at least one of the regions of interest; and generating a report based at least partially on one of the regions of interest and the annotation.