Invention Grant
US09014799B2 Transmucosal drug delivery device and method including electrically-actuated permeation enhancement 有权
粘膜下药物递送装置和方法包括电致渗透增强

Transmucosal drug delivery device and method including electrically-actuated permeation enhancement
Abstract:
Intralumenal devices and methods are provided for transmucosal drug delivery. The device may comprise a housing configured for intralumenal deployment into a human or animal subject; a drug-dispensing portion which contains at least one drug; and an electrically-actuatable portion configured to disrupt at least one region of a mucosal barrier adjacent to the housing at a selected time while intralumenally deployed in the human or animal subject. The device may be operable to dispense the drug from the housing to a region of the mucosal barrier disrupted by the electrically-actuatable portion.
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