A method for dynamically altering manufacturing routings to add, remove, or skip operations and combinations of operations within a shop floor control system in real-time to respond to current conditions. One aspect of the present invention is a computer-implemented method for dynamically generating a manufacturing production work flow. One embodiment of this method comprises receiving indication that an assembly has completed a manufacturing operation, the assembly having a work flow and a sampling strategy associated therewith; querying a data source for characteristics of a plurality of previously sampled components; querying a manufacturing floor control system for current production status; and dynamically updating the work flow for the assembly based at least in part on the sampling strategy, characteristics of the plurality of previously sampled components, and the current production status.