Invention Grant
- Patent Title: Capsule and powder formulations containing lanthanum compounds
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Application No.: US14507551Application Date: 2014-10-06
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Publication No.: US09023397B2Publication Date: 2015-05-05
- Inventor: David Pierce , Josephine Christine Ferdinando , Peter Neil Davies
- Applicant: Shire LLC
- Applicant Address: US KY Florence
- Assignee: Shire LLC
- Current Assignee: Shire LLC
- Current Assignee Address: US KY Florence
- Agency: Frommer Lawrence & Haug LLP
- Main IPC: A61K33/24
- IPC: A61K33/24 ; A61K47/02 ; A61K47/36 ; A61K9/14 ; A61K9/48

Abstract:
The present invention includes an oral pharmaceutical capsule comprising a shell, lanthanum carbonate or lanthanum carbonate hydrate, and a lubricant such as talc, wherein the shell encapsulates the lanthanum carbonate or its hydrate and the lubricant. Capsule shells comprise, for example, gelatin. The present invention also includes an oral pharmaceutical powder comprising lanthanum carbonate or lanthanum carbonate hydrate and a pharmaceutically acceptable excipient. The oral pharmaceutical capsules and powders of the present invention can be administered to treat a patient at risk of or suffering from hyperphosphatemia, at risk of or suffering from chronic kidney disease (CKD), at risk of or suffering from soft tissue calcification associated with CKD, or at risk of or suffering from secondary hyperparathyroidism.
Public/Granted literature
- US20150030695A1 CAPSULE AND POWDER FORMULATIONS CONTAINING LANTHANUM COMPOUNDS Public/Granted day:2015-01-29
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