Invention Grant
- Patent Title: Compounds that are ERK inhibitors
- Patent Title (中): ERK抑制剂的化合物
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Application No.: US14353381Application Date: 2012-10-25
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Publication No.: US09023865B2Publication Date: 2015-05-05
- Inventor: Jongwon Lim , Elizabeth Helen Kelley , Joey L. Methot , Hua Zhou , Alessia Petrocchi , Umar Faruk Mansoor , Christian Fischer , Brendan O'Boyle , David Joseph Guerin , Corey E. Bienstock , Christopher W. Boyce , Matthew H. Daniels , Danielle Falcone , Ronald D. Ferguson , Salem Fevrier , Xianhai Huang , Kathryn Ann Lipford , David L. Sloman , Kevin Wilson , Wei Zhou , David Witter , Milana M. Maletic , Phieng Siliphaivanh
- Applicant: Jongwon Lim , Elizabeth Helen Kelley , Joey L. Methot , Hua Zhou , Alessia Petrocchi , Umar Faruk Mansoor , Christian Fischer , Brendan O'Boyle , David Joseph Guerin , Corey E. Bienstock , Christopher W. Boyce , Matthew H. Daniels , Danielle Falcone , Ronald D. Ferguson , Salem Fevrier , Xianhai Huang , Kathryn Ann Lipford , David L. Sloman , Kevin Wilson , Wei Zhou , David Witter , Milana M. Maletic , Phieng Siliphaivanh
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Richard S. Parr; Laura M. Ginkel
- International Application: PCT/US2012/061836 WO 20121025
- International Announcement: WO2013/063214 WO 20130502
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/437 ; C07D471/04 ; C07D519/00 ; A61K31/444 ; A61K31/4545 ; A61K31/4709 ; A61K31/496 ; A61K31/501 ; A61K31/506 ; A61K31/5377 ; A61K45/06

Abstract:
Disclosed are the ERK inhibitors of formula (1): and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1).
Public/Granted literature
- US20140296203A1 NOVEL COMPOUNDS THAT ARE ERK INHIBITORS Public/Granted day:2014-10-02
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