Invention Grant
- Patent Title: Nucleic acid complexes
- Patent Title (中): 核酸复合物
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Application No.: US13578625Application Date: 2011-02-11
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Publication No.: US09024005B2Publication Date: 2015-05-05
- Inventor: Michael McArthur
- Applicant: Michael McArthur
- Applicant Address: GB Norwich
- Assignee: Procarta Biosystems Ltd
- Current Assignee: Procarta Biosystems Ltd
- Current Assignee Address: GB Norwich
- Agency: Knobbe, Martens, Olson & Bear LLP
- Priority: GB1002413.1 20100212
- International Application: PCT/GB2011/050263 WO 20110211
- International Announcement: WO2011/098829 WO 20110818
- Main IPC: C07H21/04
- IPC: C07H21/04 ; A61K47/48 ; A61K38/12 ; A61K38/17 ; C12N15/113

Abstract:
The present invention relates to complexes of transcription factor decoys, their delivery to bacteria and their formulation. In particular, the present invention resides in an antibacterial complex comprising a nucleic acid sequence and one or more delivery moieties selected from quaternary amine compounds; bis-aminoalkanes and unsaturated derivatives thereof, wherein the amino component of the aminoalkane is an amino group forming part of a heterocyclic ring; and an antibacterial peptide.
Public/Granted literature
- US20130059775A1 Nucleic Acid Complexes Public/Granted day:2013-03-07
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