Invention Grant
US09024022B2 Substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof
有权
O6-烷基鸟嘌呤-DNA烷基转移酶的底物及其突变体
- Patent Title: Substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof
- Patent Title (中): O6-烷基鸟嘌呤-DNA烷基转移酶的底物及其突变体
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Application No.: US13120197Application Date: 2009-09-22
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Publication No.: US09024022B2Publication Date: 2015-05-05
- Inventor: Emmanuel Bourrier , Michel Laget , Laurent Lamarque , Norbert Tinel , Eric Trinquet , Hervé Bazin
- Applicant: Emmanuel Bourrier , Michel Laget , Laurent Lamarque , Norbert Tinel , Eric Trinquet , Hervé Bazin
- Applicant Address: FR Gif Sur Yvette Cedex
- Assignee: Cis Bio International
- Current Assignee: Cis Bio International
- Current Assignee Address: FR Gif Sur Yvette Cedex
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: FR0856409 20080923
- International Application: PCT/FR2009/051787 WO 20090922
- International Announcement: WO2010/034931 WO 20100401
- Main IPC: C07D473/18
- IPC: C07D473/18 ; C07D239/47 ; C07D403/14 ; C07D487/18 ; C07D519/00
Abstract:
The invention relates to compounds of formula (I′): in which A, L2, M and B are as defined in the description. These compounds are substrates of O6-alkylguanine-DNA alkyltransferase and mutants thereof.
Public/Granted literature
- US20110236952A1 NOVEL SUBSTRATES OF O6-ALKYLGUANINE-DNA ALKYLTRANSFERASE AND MUTANTS THEREOF Public/Granted day:2011-09-29
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