The present application relates to a cascaded H-Bridge medium voltage drive, a power cell, and a bypass module thereof, wherein the bypass module is configured for bypassing a major circuit module of the power cell, while the major circuit module comprises a fuse, a rectifier, a bus capacitor and an H-Bridge inverter, two points led from the H-Bridge inverter being configured as a first output end and a second output end; a bypass circuit comprises a first bridge arm and a second bridge arm; a point led from the first bridge arm is configured as a first input end of the bypass circuit, a point led from the second bridge arm is configured as a second input end of the bypass circuit, and the first input end is electrically connected with the first output end, the second input end is electrically connected with the second output end.