A motion guide device including a track shaft having a rolling surface; a moving member movable along the track shaft; a first seal member in sliding contact with a surface of the track shaft to close a gap between the track shaft and the moving member; and a second seal member provided along the rolling surface of the track shaft and closes the gap between the track shaft and the moving member. The second seal member includes: a fixing substrate locked to the moving member; and a seal portion fixed to the fixing substrate along the rolling surface of the track shaft and includes a seal lip portion in sliding contact with the surface of the track shaft and an extended seal portion in close contact with the first seal member while being compressed by the first seal member when the first seal member is fixed to the moving member.