Disclosed are a syringe capable of measuring an inner temperature of a patient body and a method of manufacturing the same. In the syringe, a different metal from that of a syringe needle is deposited on an inclined surface of a tip portion of the syringe needle to form a thermocouple junction with the metal of the syringe needle, whereby the region causing pain in a patient body can be diagnosed while allowing administration of medicine thereto, thereby enabling efficient treatment and significantly reducing potential harm due to drug abuse.